Zinc dopamine reddit. I suggest the glycinate form.

Zinc dopamine reddit Amen low dopamine is related to attention problems. BUT: When you first start taking zinc, it might make you feel like it's having the opposite effect. I've seen many threads on reddit regarding this form of zinc and such reaction. That is made of distilled water, ethyl alcohol, zinc sulfate and b6 p5p Highly recommend taking a methylated b-complex, (or b2 and p5p at the least) Molybdenum, Zinc Glycinate, and Selenium (2 Brazil nuts covers selenium needs) Glycine (3g a day before bed) and Vitamin C and/or PQQ, in order to cover all of the cofactors NAC needs and prevent side-effects. Dopa, a precursor of dopamine is oxidatively produced from tyrosine by the copper enzyme tyrosinase. Tonic dopamine is the rather constant background level, whereas pulsatile are the brief spikes due to some stimulus. So, a 50mg tab of zinc gluconate would be roughly 7mg of elemental zinc. It is also anecdotally reported to give people vivid dreams and a significant increase in appetite, 2 effects commonly seen in people who use dopamine agonists. ZMA is not really a good product. Magnesium Glycinate - 400-600mg / day split over day. High doses of zinc long-term can cause copper deficiency and vice versa. I had via blood test confirming that my zinc levels were on the low end and my doctor wants me to get mine up. Increased dopamine receptor density is not necessary for the upregulatory action of Bromantane. According to a 2021 study, zinc helps elevate levels of brain-derived neurotrophic factor (BDNF) in the areas of our brain that control our emotions. Novos labs longevity protocol says to take them separately because they compete for similar pathways. L-tyrosine or N-acetyl-l-tyrosine are better options that will effectively raise dopamine levels and are safe to supplement long-term, although work even better when cycled. A DRI the mechanism of action at the dopamine transporter (DAT) for dopamine releasers/substrates is entropy-driven (i. Excess copper leads to higher epinephrine production, tanking dopamine. Evidence of this speculation is found with the shared symptoms that result from individual nutrients that have similar effects on specific neurotransmitters (ex. I normally don't drink coffee. If you maintain this for several weeks your receptors will increase their sensitivity to return you to baseline. minerals: zinc 20 mg, copper 2 mg (10% of zinc amount to prevent copper depletion, although Cu is an oxidant), selenium 100 mcg endogenous compounds: acetyl-carnitine (ALCAR) 1000 mg, lipoic acid 600 mg, ubiquinol (CoQ10) 100 mg, beta-alanine 1600 mg been struggling with severe morning groginess and brain fog for years. I don’t get how people actually benefit from it. I think zinc is known to boost dopamine for one which would 100% cause a rise in anxiety. However, we recognize that many people want to discuss how they feel the research relates to their own personal lives, so to give people a space to do that, personal anecdotes are now allowed as responses to this comment. Taking a single shot of sulbutiamine increases dopamine release. The bioavaliabilty of zinc supplements is very low, as little as in the teens depending on type, and the all vary. Dopamine is considered to be associated with tons of other effects that have to do with the bigger result of pleasure/euphoria and also more random ones, such as anticipation, repeating behavior, muscle contraction, and more; essentially it plays a big role in the cycle/process of the concept of "reward". In addition, zinc supports one of the fundamental ingredients for mental health — dopamine. AlphaGPC is the one for Acetylcholine, but it does have an unfortunate side-effect because if you take it every day, it feeds some “bad” bacteria in your gut biome, that convert Choline into mildly toxic TMAO. But even one dose now completely obliterates my dopamine system. Have had that experience with both Vyvanse and Dexamphetamine Dopamine based stimulants will deplete your Sodium levels so make sure you're getting enough of your electrolytes; Sodium, Potassium etc. Zinc inhibits prolactin in the CNS, increases thyroid hormone activity and antagonizes NMDA receptors. My parents didn't place much stock on it, who needs zinc right, certainly not a 6 year old! I've honestly felt better on Zinc and Iron supplements, my severe PMS almost vanishes, my mood improves, I don't suffer frequent burnouts, I'm more focused and I'm not fatigued. The link is strong enough that the degree of zinc deficency can accurately predict the severity of depression. It keeps my ratio where it needs to be, and I've only ever struggled with zinc deficiency not copper. . Evidently Bacopa acts similarly to NAC and I felt so shitty I almost tried to find a therapist. It got rid of my anhedonia, depression, anxiety and what I thought was permanent sexual dysfunction caused by SSRI treatment. and dopamine. Mar 28, 2022 · Lower levels of zinc have been linked to symptoms of depression and anxiety. So it looks like the Tory government and our crumbling health service have comprehensively hung us out to dry. For everyone out there, this doesn't mean now you should take a lot of zinc forever. Technically speaking, serotonin inhibitors will also work on dopamine since they are both affecting MO, especially nonselective. e. I'm 21, lift weights 5x a week, eat generally well and high protein, take daily vitamin d, omega 3, zinc, magnesium. Also giving blood to remove iron due to iron overload in body. Watch his video on dopamine and the analogy of the tidal wave pool. Different dopamine receptors can have opposite effects depending on their location in the synapse (pre- or post- synaptic) or in different brain regions. If you have hidden copper toxicity - excess copper stored in the tissues (i. conformational change). Assuming we're facing weeks, maybe even months without proper access to medication, I guess it's time to dust off a few of those old coping strategies. Stop doing those first and your dopamine will come back and cortisol will lower. Zinc plays a large role in how we react to stress and deficiency is linked to depression. Maybe your getting a bump in some of the more stimulating ones. Nor does zinc do anything for ADHD if you are not deficient in the mineral. Also consider also using topical DIY Zix for further non systemic topical DHT reduction. Vitex Agnus Castus, also known as Chaste berry, has long been used as a treatment for sexual disorders and insufficiency. John's Wort. 35% elemental zinc by wright. I take plenty of both zinc and copper too. Just off hand I can recall a zinc taste acuity test double blind 300 participant's that also took zinc blood plasma lvls and found the zinc taste test to be pretty damn accurate. Zinc and iron blood levels of at least 100. But vitamin c and tyrosine. Apparently (too much) zinc can affect brain dopamine binding, you can research this by googling zinc dopamine. 30mg elemental zinc appears to be slightly effective as an addition to D-amphetamine therapy. Recently I made the mistake of trying NAC and Bacopa back to back. You need to have a baseline stimuli free of bombardment. All this is good, but the problem is that while zinc is the signal for producing metallothioneins, these proteins bind to copper better than they do to zinc. Manganese is important to the thyroid as well. The RDA for Zinc is 11mg daily for adults, and the RDA for Zinc is 0. There’s 2 camps that vary in some of the subtleties but they’re both pro copper, iodine, b vitamins, real vit C and then it seems to vary on zinc & other minerals supplements depending on your body make up and general health. Why would this be beneficial if schizophrenia correlated with high dopamine in which zinc supplementation would only increase further? Nov 3, 2021 · Background Dopamine (DA) is a neurotransmitter that plays roles in movement, cognition, attention, and reward responses, and deficient DA signaling is associated with the progression of a number of neurological diseases, such as Parkinson’s disease. Although zinc is widely prometed as a life changer mineral, it's still a heavy metal and when taken in excess; you won't pee out the unnecessary amount like the case in Vitamin C. Zinc promotes gaba production (aswell as glycine) this competes with dopamine and can lower dopamine causing irritability and anger if you are already low! You can try to offset this by taking tyrosine which increases dopamine! It's a tricky & complicated balance. Just commenting for balance. Your symptoms sound like adrenal dysfunction to me. Not only is dopamine important for muscle building benefits, but it can also counteract depression. I feel incredible energy, anxiety gone, super social, sex drive sky high. According to a 2021 study, zinc does The optimal ratio is said to be anywhere between 8:1 Zinc:Copper to 15:1 Zinc:Copper; there is no universal agreement on the optimal ratio. possible its the zinc supplement reducing supply of tyrosine. Prolactin is known as the anti dopamine hormone so more dopamine offsets it's crap. “In noradrenergic neurons, Cu is needed for activity of dopamine-β-hydroxylase (DBH), which converts dopamine to norepinephrine and is required for catecholamine balance” “Cu is required for myelination of neurons [ 13 ], and it influences synaptic transmission by modulating functions of GABA and NMDA receptors, as well as voltage-gated The 4 supplements are: Zinc, Creatine, NAC and Fish Oil Zinc: Study Link. Successful antidepressant treatment can raise zinc levels. The original formula consists of mag aspartate, and aspartate is excitatory. The possible mechanism behind this effect would be the fact that picolinic acid is Dopamine beta-monooxygenase (DBM) inhibitor. Animal studies show that higher zinc levels can decrease dopamine levels by inhibiting iron. Norepinephrine–dopamine reuptake inhibitor (NDRI) , major depressive disorder, atypical antidepressant , Epileptic seizures , ADHD, alleviate sexual dysfunction, weight loss, releasing agent of dopamine and norepinephrine (NDRA), similarly to other cathinones , Wellbutrin SR and XL A common long term side effect for ashwaganda is reported to be anhedonia. In general, it was like drinking too much caffeine. Zyban. Whereas the two studies in which increased immobility time in the FST following 2 weeks of the diet utilized the zinc-deficient diet containing 0. D of 80. , 2015), but a role for zinc homeostasis with respect to clinical depression and psychosis is not well appreciated by psychiatrists. The question is asking how do people get high when the body doesn't have the resources to provide the dopamine creation the drug triggers. Do you mean dopaminergic drug addiction? You can't be addicted to dopamine, part of addiction involves dopamine dysfunction that usually arises from illness, environmental pollution, or most commonly, drug abuse. Dopamine isn't a simple variable that you can raise or lower within the brain for a desired effect. B vitamins on the other side 66 votes, 75 comments. edu Theoretically same for Zinc - Copper pair Maybe you should look into electrolytes, and drink a mix of potassium + magnesium + salt + zinc. Excess copper converts your dopamine to norepinephrine, I felt psychotic and it took a couple of days supplementing zinc alone to feel normal again. Dopamine-β-Hydroxylase has 2 cofactors copper and Vit C. α-Amidating monooxygenase (α-AE), also called peptidylglycine α-AE, uses copper and ascorbate to remove two car- bons from a C-terminal glycine of peptides, thus generating an amide. If you are low in iron (and thus reduced dopamine synthesis), be sure that you aren’t taking iron or eating iron-rich foods alongside a zinc Zinc plays a big role in neurotransmitter synthesis. I think people should search for and read the studies instead of believing the bro- nonsense that they read on reddit. I'm extremely sensitive to increases in dopamine because of some weird neurological problems I have. Symptoms of Zinc deficiency could be (not exclusive list and these symptoms could be caused other factors as well): The dopamine transporter (DAT), a membrane protein specifically expressed by dopaminergic neurons and mediating the action of psychostimulants and dopaminergic neurotoxins, is regulated by Zn(2+) which directly interacts with the protein. Dopamine addiction is not a thing. B6 as pyridoxine HCL is garbage, and P5P can also be stimulating. Zinc increases dopamine. (Over 80%) You can find liquid zinc sulfate on Amazon for like 15-20 bucks. So my muscles got tense and I had trouble sleeping. As a neurotransmitter, dopamine enables the mind and muscle to work together, increasing the benefits that occur from weightlifting. There are two 'types' of dopamine: tonic and pulsatile. true. Anyways, stick with those precursors and then stay off of tv and your phone. This is based on a group that supplements 5mg+ per day. Also per Dr Amen in order for a person to make dopamine you need optimal levels of zinc, iron and D. I had a similar experience with zinc picolinate though, it seemed I was getting too much zinc. Dopamine reuptake inhibitors, on the other hand, are unable to cause euphoria, even if they are injected in very high doses. Vitamin B6 P5P form - Required for both serotonin and dopamine Zinc Picolinate - but be careful - you can take too much. This is a good reminder that if you are taking zinc as a supplement, it can interact with iron absorption. According to this study, high dose Zinc supplementation (60ppm in drinking water, equal to 60mg per day in humans) does not change brain zinc at all: Mice fed high dietary zinc showed significantly increased zinc level in serum and hemocytes, but the total brain zinc level was not changed. to get 20 mg of zinc can take upwards of 200 mgs of zinc supplements and if your doing that then throw in some copper Jun 29, 2017 · Introduction. Zinc will regulate copper levels. Remember the copper-zinc inverse relationship regarding their absorption. This community is focused on neuroscience research of how autism, ADHD, OCD, schizophrenia, schizoaffective etc presents in women. I have heard of selective SSRI in high dosage affecting dopamine. 10/1 seem ok for some, others do well all the way down to 1/1 ratio. This way, simple things will give you the dopamine boost. Zinc antagonizes copper - you might be feeling the effects of the copper being stirred up and overstimulating the nervous system. The study is specifically with cocaine addicted mice, and basically zinc made them do more coke than usual (presumably because it made it better, dopamine is the best part of coke). Done sleep studies and blood tests (only high creatinine and familial cholesterol). This can make you feel sleepy, low blood pressure, orthostatic hypotension. iirc zinc has positive effects on dopamine signaling. Your common SSRI that is probably the most effective is St. Folate upregulating production of dopamine and zinc inhibiting dopamine reuptake; the result being the same negative feeling). ---nap . Not recommended. liver, kidneys, brain), then that be affected by taking zinc. Additionally, zinc is a fairly easy nutrition to obtain from food. , 2014; Nowak, 2015; Prakash et al. Per Dr. hydrophobic), whereas for dopamine re-uptake inhibitors it is enthalpy-driven (i. Long-term L-Dopa supplementation has potential to downregulate Dopamine synthesis. A dopamine releasing agent (DRA) is a type of drug which induces the release of dopamine in the body and/or brain. In large amounts, monoamine releasing agents tend to be neurotoxic. Copper supplementation is necessary to prevent deficiency when supplementing high dose zinc, however at 30mg zinc per day you should be fine. Dopaminergic Neurotransmission. Still, both are significantly different than what is in the brand you have been taking. Like zinc gluconate is 14. The fact that you are vegan won t make you automatically deficient in zinc if you eat legumes and nuts. Each form has a different conversion to elemental zinc. Can attest myself after several years on and off. Zinc is an essential trace element required by all organisms for various biological processes. On a side note, I’ve tried zinc for many years and always had to come off because it would cause side effects. When you get your dopamine, research increasing dopamine receptor density. 20 mg of zinc is very little. "The human dopamine transporter contains a high affinity extracellular zinc binding site which, upon zinc binding, inhibits dopamine reuptake and amplifies amphetamine-induced dopamine efflux in vitro. g. Summary: Bromantane increases dopamine synthesis, balances excitatory and inhibitory neural networks, and increases neurotrophins by reducing neuroinflammation through epigenetic mechanisms. It's actually not necessarily paradoxical - Zinc potentiates dopamine release by Amphetamine (through DAT allosteric modulation), but at the same time, it might also decrease dopamine production (through inhibition of iron binding to TH). IT is a rate iimited dopamine precursor. This could lead to a higher conversion from Dopamine to Norepinephrine and can be counteracted by supplimenting Zinc. Slow COMT is associated with high tonic dopamine. DBM normally converts dopamine to norepinephrine. There's an entire book out there just about this relationship and all the chaos that follows up when imbalanced. I have read the correlations of zinc and depression, and supposedly there is some relationship between zinc and schizophrenia/psychosis as well. Copper and Zinc are Antagonists, a lot of stress and depression can deplete Zinc. Cocaine appears to lower your zinc levels, that's why supplementing seems to help. Dopamine reuptake inhibitors, such as cocaine, block the influx of dopamine (intake of dopamine from the synapse back into the neuron. Dopamine is a neurotransmitter involved in the motivation and reward pathways. " Having Zinc at the same time as your meds will definitely potentiate Adderall. Take it with your adderall for a better peak and easier comedown, or take it as the last adderall is wearing off in order to mitigate the comedown almost entirely. My mother took it (because her doctor told her to) when she was dying from cirrhosis of the liver. Using co-forms of zinc that have other uses in the body like zinc sulfate, (which you are) and zinc glycinate instead of zinc picolinate or zinc gluconate is superior as picolinate & gluconate are worthless binding agents once cleaved from the zinc in digestion. I started taking a zinc+copper supplement and felt more energy at first, but quickly become overloaded in copper and became extremely irritable. Are you sure that's the problem? If you absolutely are sure, then check your zinc/copper levels. Certain pairs of things need to be kept balanced in the body, such as zinc-copper or dopamine-serotonin. Last time this happened only time fixed it. yeah my first panel showed a slight deficiency in both zinc and copper, i started zinc and watched my copper deficiency get worse so i began taking 2mg copper bisglycinate alongside (but at different times) 30mg zinc picolinate. Perfect! Then definitely don’t take extra zinc. like not nearly enough. These epithelial cells shed every 5-6 days, and the metallothioneins with their bound excess zinc are shed too, and excreted in feces. I read that max zinc per day is 30-40mg Zinc binds to the dopamine transporter and slows it down, allowing dopamine to remain active in the synapse for a longer period of time before being pulled back into the cell to be recycled. I would strongly recommend trying those before trying SAM-e. Nov 13, 2021 · The link between iron and zinc supplementation and the observed decrease in ADHD symptoms in the controlled clinical trials selected for this systematic review also makes sense with regard to the role of zinc and iron as dopamine reuptake inhibitors, which was precisely the core target of the stimulant medications used in the combined treatment Zinc increase dopamine and testosterone and both can increase arousal even in non deficient people . I use zinc, b6, and tyrosine for anti prolactin. This makes the pulses of dopamine small in comparison. 326,327 Importantly, zinc may inhibit neuronal NMDA glutamate receptors, which are dysregulated in those with depression, and raise BDNF levels, which can promote neuroplasticity TL;DR: Zinc potentiates Cocaine in mice; low-Zinc diets attenuate Cocaine's stimulant action - human Cocaine users with low Zinc levels consume more Cocaine, perhaps to cover up for a possible dopamine deficit created by a low Zinc level. Creatine: Study Link Yeah but that dopamine isn't from the drug it's from the drug interacting with your body to trigger dopamine's creation. Hello everyone, In the episode about dopamine,Huberman says that you can raise your base line “wavepool” of dopamine by taking a cold shower. Feel amazing after pmo as opposed to depressed, with brain fog etc. Supplementing zinc has made me feel great. Does the zinc you used contain vitamin B6 also, by the way? Welcome to r/science!This is a heavily moderated subreddit in order to keep the discussion on science. RDA of zinc is 11mg, no one needs that much zinc. Zinc is also important to thyroid. Herein, we report a host-cell-specific direction of the Zn(2+ … Dec 27, 2024 · I got 160mg of zinc citrate supps of which 50mg is elemental zinc but that seems too high. A daily intake of 60 mg of zinc for 10 weeks (10 mg from the diet and 50 mg from a zinc supplement) was associated with a decrease in copper status. But I could not find anything suggesting there is such a variant. Magnesium is helpful. That along with too much cortisol. There are no studies that point to an increase in dopamine or noradrenaline due to concurrent zinc supplementation. I don’t know exactly how it does it even though it does increase dopamine in the short term, but the side effect is is common enough it’s become a trend among teens to use it as a way to become apathetic. They do this in part by reversing the DAT, so that rather than shuttling dopamine back into the neuron, it transports dopamine out of the neuron. My sensory processing sensitivities become more manageable. Take 1g a day. Zinc is also said to be stimulating as it is possibly a weak dopamine reuptake inhibitor. I did seem to have an increase in mood (or I should say a reduction in negative mood), but noticed I was putting on water weight. The enzyme that converts L-DOPA into active dopamine, L-dopa decarboxylase, is a pyridoxine-5'-phosphate (PLP) dependent enzyme and due to the actions of pyridoxine infusion paralleling that of dopamine (in regards to prolactin and growth hormone) it is thought that additional pyridoxine increases the activity of this enzyme particularly in the hypothalamus. Jarrow Zinc Balance is a nice low dose of zinc and copper 15mg:1mg. 😊 We discuss the wonderful ways the autistic brain functions! Zinc is a surprisingly effective supplement as well, and actually is a subtle dopamine re-uptake inhibitor. If both occur at the same time, though, Amphetamine could deplete dopamine stores faster. I suggest the glycinate form. However, it wasn't until recently that scientists examined the compounds in the plant and discovered that many of them can reduce prolactin as much as dopamine itself (7). These support the metabolic pathways for serotonin and catcecholamine synthesis (dopamine, noradrenalin, etc) I took a few weeks off it and supplemented with zinc and copper and eventually felt normal. I normally have severe social anxiety and symptoms of CPTSD. Zinc has completely changed my life. Furthermore, zinc supplementation is well known to boost testosterone. The only one that I know of is extract from Nightshade plant. They might be better for people with addictive personalities. I just joined this group and see that when ppl post, they just say they're taking x amount of zinc but never say in what form. Keep in mind you also get zinc from foods as well, so you are likely overdosing on zinc without even realizing. I couldn’t get my copper levels up to “in range” so i just settled on a 15mg zinc glycinate daily Drugs like ecstasy or molly blow all your dopamine levels and take many days to replenish. 37 mg zinc/kg and the zinc-adequate diet containing 52. Also there’s zinc lozenges and cold medicine! Edit: missing word I've recent been taking Maca and the effects have been huge for me. I’ve done this and it’s worked great but… I was wondering what are some other ways you can increase your dopamine naturally ? I’m really struggling to focus these days even though I’m on Fatigue can be caused through multiple pathways: 1- Lower norepinephrine due to low Dopamine Beta Hydroxylase activity (a Copper enzime that tranaforms dopamine into norepinephrine). It is essentially a natural “dopamine reuptake inhibitor. ” Zinc has a multitude of functions in the body, including reducing oxidative stress, modulating neurotransmitter receptor function, and regulating gene expression. 8 mg zinc/kg [21, 68], similarly, we utilized the following diets: zinc-deficient 3 mg zinc/kg; zinc-adequate 50 mg zinc/kg , the study which did I took 40 mg of combined zinc biglycinate + zinc picolinate, and I have seen a pretty alarming decline in work motivation. Get the Reddit app Scan this QR code to download the app now Zinc can cause a one-time spike in dopamine levels if you've been mildly or moderately deficient. Or - might be much better - make sure to eat daily 2 tomatos + 1 avocado + 1 paprika + 1 leaf of bok choy + water + salt + eat good meat / fish = and never worry about taking any supps again There’s a couple groups that are promoting copper due to deficiencies. The fact that dysfunction of the dopamine transporter is involved in the pathogenesis of … A plausible explanation is that 5-10% of people of sensitive to supplements and can have strong reactions. This is a good thing, as it prevents zinc toxicity. Obviously 30 mg is less than the 50 mg tested in the study and is also within the upper limit dose of 40 mg of zinc a day for adults outlined by The National Institutes of Health. You can find studies where taking 3 mg of zinc daily reduces the amount of dexamphetamine you have to take to get the same results by 30 %. Jan 16, 2025 · Zinc to Copper ratio of 15/1 seem to deplete Copper. basically disfunctional until 1-2 pm. Probably not. Zinc gluconate has been much more effective for me. Dopamine releasers cause euphoria in high doses and therefore might pose a risk for people with addictive personalities. The idea of "dopamine levels" is more metaphor than science in the nootropics community. The only time to take extra zinc would be at the onset of cold/flu symptoms, and that’s only to lessen the severity/length of the cold/flu. dopamine, serotonin), which some people seem to be unable to properly regulate. That is how you start feeling those weird feelings. Increasing your daily zinc intake can help improve symptoms. It seems like maybe I need it the most but just need to start off smaller because 8 mg made me feel kryptonited. Zinc may potentiate Cocaine by faciliating its binding to DAT. The dopamine transporter is regulated by zinc (Zn2+), which directly interacts with the transporter protein as a potent non-competitive blocker of substrate translocation (dopamine transport inward and outward). 9mg for adults. But I also don't know how dopamine would be low and norepinephrine would be high unless the enzyme DBH - which converts dopamine to norepi - had some variant which upregulates the conversion rate. Your symptoms are possibly what people refer to as "overmethylation". Hi, we likely have the same issue. Continuous use reduce average dopamine levels. Due to its critical functions, DA expression levels in the brain are tightly controlled, with one important and rate-limiting step in its According to this study, 30mg elemental zinc daily for 13 weeks (final five weeks used alongside D-amphetamine) was able to reduce the amount of D-amphetamine that was needed by 37% and reduced affective blunting from 21% (placebo with amphetamine) to 11%. B-vitamins generally increase methylation levels (the outlier here would be B3) and, in turn, raise monoamine levels (e. I took 8 mg and it was way too strong for me. I started taking 50 mg of P5P at my doctor's recommendation in order to increase dopamine; B6 is a major cofactor for speeding up the enzyme that converts l-dopa to dopamine but also histidine to histamine. Helps Produce Dopamine. The results of the present study indicate that zinc supplementation together with SSRIs antidepressant drug improves major depressive disorders more effectively in patients with placebo plus antidepressants (SSRIs). May in my case would be worth trying aswell, one of the most basic approeches. L-Tyrosine is my goto/must have for keeping my Dopamine reward system working optimally. The There are a number of ways zinc does this, but some of these include: •prevents your brain from becoming overexcited at NMDA receptors •helps create/regulate serotonin, GABA, dopamine •increases BDNF According to Trudy Scott, the zinc taste test can help determine if you need zinc! Google it! The symptoms of Autism include a lack of willingness to make eye contact, repeated tasks etsWhich some studies were ameliorated with glycine, arginine, zinc, and creatine ( I can't find the study at the moment)My current stack is: Lysine, acetyl L carnitine, COQ10, Zinc, selenium, vitamin C and Iron ( every two days) and probiotics For example, a Harvard article titled "Nutrition's dynamic duos" discusses the effects of high amounts of zinc causing copper deficiency so they recommend adding copper to zinc supplements. You end up in higher dopamine state after DBM inhbition. What others do YOU know? Little educational post attempt here, let's all share our knowledge on this to help each other out. Ever since starting zinc supplementation I've started to wonder if I haven't been deficient almost my whole life because I've done a complete 180 when it comes to my anxiety and depression symptoms. Also there are distinct metabotropic receptors that bind zinc in the brain and an immediate search pulls up a journal article that mentions it has interactions with AMPArs and 5HT1Ars + mTOR among other places. Its general actions are well reviewed, as briefly described in this paper and several excellent reviews (Marger et al. In all honesty, it probably only makes a difference if you're a regular user. Here are some reasons why zinc could work for social anxiety or hesitation: Zinc deficiency and anxiety: Low levels of zinc have been linked to symptoms of depression and anxiety. Most common is 3/1 to 5/1. I cut one 25mg pill to half and take a half every day, that’s all you need. After cessation of daily dosing, your dopamine levels will increase, but the sensitization will last for a few months. poyotrnf mqipq lubesa krkq iuqj yayryt epicpic ngzba gtrcxbfy pscqq atwij nwdp rxcso qaklmqi xyvnort